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In a randomized, controlled, double-blind study with 203 patients, applications of a 10% comfrey cream were well tolerated, reduced swelling and pain, and improved mobility (Kucera et al., 2004). Some of these components are thought to speed up wound healing by stimulating new cell growth. This soothing blend of herbal oils contains Comfrey (also known as Knitbone) and Eucalyptus Oil. 2016 Jan;41(2):116-33. doi:10.1097/01.brs.0000249525.70011.fe. Pharmazie 1995;50:83-98. Latest: Senior Software Engineer - Front End Senior Software Engineer Senior Product Manager - Basket, Checkout and Payments UX Designer - Instore Tech. Toe was infected and painful. Limited trials have evaluated the effectiveness of alkaloid-free preparations for external use; however, these studies did not examine how much liver damage occurred in patients. 2013;27(6):811-7. There is no daily recommended allowance for comfrey, sold in creams, ointments, gels, and salves. Experts suggest not using comfrey cream for longer than ten days in a row. View abstract. The recipe makes about 6 small jars. Combination of comfrey root extract plus methyl nicotinate in patients with conditions of acute upper or low back pain: a multicentre randomised controlled trial. Medicinal use of this product has not been approved by the FDA. These third-party organizations test products to ensure they were manufactured safely and contain the ingredients indicated on the labeling without contaminants. Acupuncture has also shown solid evidence of benefit for back pain. Using a supplement like comfrey may have potential side effects. Herbal medicine for low back pain: A Cochrane review. Although not all side effects are known, comfrey is thought to be possibly safe when applied to unbroken skin for less than 10 days. Other uses not proven with research have included skin wounds, skin ulcers, cough, sore throat, gum disease, joint pain, diarrhea, and other conditions. The study involved 43 patients with knee osteoarthritis and a six-week treatment period. If your healthcare provider recommends it, make sure to use it on intact skin for a small amount of time, and be careful that infants do not ingest it. Turn off heat and give it a good stir. J Chiropr Med. Consult your healthcare provider before using. Sometimes, massaging on topical ointments can help reduce pain and inflammation. Nat Prod Res 2018;32(5):605-9. doi: 10.1080/14786419.2017.1326492. Find out how to use it here along with its benefits. View abstract. Version: 5.01. Shop buy 1 get 1 half price on all gut health products, Buy 1 get 1 Half Price | Plus an extra 20% off 25, App Exclusive | Get an extra 22% off 25 when you spend on the H&B App, Royal Mail strikes may cause a delay to our click and collect service, Looking for fitness advice & inspiration this New Year? Bleakley, C. M., McDonough, S. M., and MacAuley, D. C. Some conservative strategies are effective when added to controlled mobilisation with external support after acute ankle sprain: a systematic review. Three clinical studies have provided evidence that ointments containing comfrey root have helped reduce back pain. Herbal medicine for low back pain: A Cochrane review, Dietary Supplements: What You Need to Know, Sinusoidal obstruction syndrome (blockage of veins in the liver). Can quickly relieve muscle and joint pain. (2018). Stop using comfrey and call your healthcare provider at once if you have: liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Centurian, South Africa: Medpharm Scientific Publishers. Comfrey should not be used in place of medication prescribed for you by your doctor. The combination of Vitamin E, Wheat Germ oil and Rice Bran oil makes this cream perfect for your daily hydration needs. Koll R, Klingenburg S. [Therapeutic characteristance and tolerance of topical comfrey preparations. Symphyti) in the treatment of ankle distorsions: Results of a multicenter, randomized, placebo-controlled, double-blind study. Comfrey - The Lost Herbs A systematic review and quality assessment of case reports of adverse events for borage (Borago officinalis), coltsfoot (Tussilago farfara) and comfrey (Symphytum officinale). The ointment has a very mild herbal fragrance and is soothing on application. Please review this supplement label with your healthcare provider to discuss potential interactions with foods, other supplements, and medications. Barthomeuf, C. M., Debiton, E., Barbakadze, V. V., and Kemertelidze, E. P. Evaluation of the dietetic and therapeutic potential of a high molecular weight hydroxycinnamate-derived polymer from Symphytum asperum Lepech. 2004;11(6):470-477. Set aside cup for the cream recipe and store the rest in a glass jar. Navarro VJ, Khan I, Bjrnsson E, Seeff LB, Serrano J, Hoofnagle JH. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. ). Store at room temperature away from moisture and heat. doi:10.1002/14651858.CD010538, Smith DB, Jacobson BH. After 7 years in this role and a further year working as a drug safety officer in the pharmaceutical industry, Bhupesh joined Holland &Barrett as a Senior Regulatory Affairs Associate in 2019. Registered office: Samuel Ryder House, Barling Way, Nuneaton, Warwickshire CV10 7RH. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. 1. Add comfy to Vaseline . Soaked foot in warm water with a few leaves of comfry. While larger and more studies are needed to fully determine safety and effectiveness, short term topical application of comfrey may give you peace of mind, relief, and support while you rest and heal, following any additional advice from your physician. Grube, B., Grunwald, J., Krug, L., and Staiger, C. Efficacy of a comfrey root (Symphyti offic. Check regularly, but it should take about six weeks for all the leaves to break down into a thick, black liquid. COMFREY: Overview, Uses, Side Effects, Precautions - WebMD Dosage: How Much Comfrey Cream Should I Use? A member of the borage family, comfrey root, leaves, and stems have an obvious coat of bristly hair. A handbook for practice on a scientific basis. This comfrey cream recipe works great for local areas that have mild bruising or soft tissue pain. cup organic, unrefined cocoa butter Patients with hypersensitivity or allergic reactions to the plant should also avoid external use. It is easily absorbed to leave your skin feeling fresh, soft and radiant. Like any new treatment, discontinue use if any irritation occurs. (Grube et al., 2007). 12 drops peppermint (Mentha piperita) essential oil Phytomedicine, 14(1), 2-10. https://doi.org/10.1016/j.phymed.2006.11.006, Jedlinszki, N., Balzs, B., Csnyi, E., & Csupor, D. (2017). We're proud to make a difference, and you can to. Comfrey contains chemicals that cause serious liver damage when taken by mouth. Palestrica of the Third Millennium Civilization & Sport, 14(3). The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Kuera, M., Barna, M., Horek, O., Kovrikov, J., & Kuera, A. This recipe is contraindicated for small children and those with certain medical conditions. Available at: https://www.cfsan.fda.gov/~dms/dspltr06.html. Instructions. , 43 volunteers with osteoarthritis used either a topical cream containing comfrey, tannic acid, and eucalyptus or a placebo cream 3x/ day for 6 weeks. Some people ingest comfrey roots or leaves or use them in teas. The internal or extensive topical use of comfrey cannot be recommended because of numerous reports of liver damage. Wien Med Wochenschr. What alternatives to comfrey cream are there for back pain? Fortschr Med Orig 2002;120:1-9. Lewis, C. J. FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. Centurian, South Africa: Medpharm Scientific Publishers. Comfrey cream, an topical herbal product, is thought to reduce inflammation and pain when applied to the skin. Comfrey Oil: Benefits, Uses & Risks | Holland & Barrett Comfrey may have been applied to the skin in a specific preparation to treat some of these conditions. comfrey cream holland and barrett. Grube, B., Grnwald, J., Krug, L., & Staiger, C. (2007). Comfrey can kill. Wien.Med.Wochenschr. The following applications have been used in research: Using large amounts of comfrey cream or using it for extended periods of time increases the risk of side effects like liver toxicity. Huxtable RJ, Awang DV. Osteoarthritis.Cartilage. 20 Rewards for Life points with this purchase, Potters Herbals Comfrey Ointment is a traditional herbal medicinal product used for the symptomatic relief of minor sprains and bruises, based on traditional use only. It has bell-shaped red-violet or yellowish flowers. 2758955. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. This is not a complete list of side effects and others may occur. 2014;20(4):347-55. Many have said that it has helped them with a variety of aches and pains! Comfrey [Online article]. One study followed 142 patients with ankle sprains. 2012;62(6):285-289. Kucera, M., Barna, M., Horacek, O., Kovarikova, J., and Kucera, A. Efficacy and safety of topically applied Symphytum herb extract cream in the treatment of ankle distortion: results of a randomized controlled clinical double blind study. Swiss.Med.Wkly. Influence of moderate physical exertion on subacute low back pain, after Symphytum officinale ointment treatment. Study results revealed that pain intensity during active movement decreased an average of 95.2% in the group given comfrey ointment. Skip the missed dose if it is almost time for your next scheduled dose. View abstract. A symptomatic treatment of minor sprains and bruises. It contains chemicals that are poisonous. Need some help with an order or want to speak to a member of our Customer Services team? Although not examined in clinical trials, comfrey may possess antifungal and anticancer activity. Two interesting studies found that a topical application of a product containing comfrey root extract helped with knee pain and stiffness. Comfrey contains chemicals called. Although it has historically been used on open wounds, it is now not advised related to the toxic pyrrolizidine alkaloids that can absorb more readily into the body through an open wound. Knee pain and stiffness can be a stubborn concern that keeps many from doing activities they enjoy. . Regulatory Toxicology and Pharmacology, 83, 1-4. https://doi.org/10.1016/j.yrtph.2016.11.015. All rights reserved. 2005 - 2023 WebMD LLC. DOI:10.1211/PJ.2021.1.69803. Lorem ipsum dolor sit nulla or narjusto laoreet onse ctetur adipisci. Adv.Ther 2000;17(4):204-210. WebMD does not provide medical advice, diagnosis or treatment. Stop using comfrey and call your healthcare provider at once if you have: liver problems-- nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Would you like to win our brilliant Botanical Business Package with nearly $1,000 in prizes? Comfrey is not recommended for internal use because of the liver damage caused by its pyrrolizidine alkaloids. This site uses cookies to improve your experience. Join Rewards for Life today and we'll give you 300 points worth 3, Save 5% on your favourite products, plus get the lowest price from the last 90 days and free delivery on orders over 10. Penetration of lycopsamine from a comfrey ointment through human epidermis. Looks like you may need to upgrade your browser We're sorry, we no longer support the web browser that you are using Begin mixing on low. Select a condition to view a list of vitamins. *PR sample. British Homeopathic Journal, 90(01), 21-28. https://doi.org/10.1054/homp.1999.0460. 98% Naturally derived. Z Phytotherapie 2000;21:127-134. However, comfrey can also contain toxic substances called pyrrolizidine alkaloids that cause liver damage, cancer, and death. Thank you, {{form.email}}, for signing up. View abstract. . Researchers have investigated the effects of comfrey cream on several health conditions. British journal of sports medicine, 44(9), 637-641. https://doi.org/10.1136/bjsm.2009.058677, Grube, B., Grnwald, J., Krug, L., & Staiger, C. (2007). Molecules. Additionally, use on a deep cut may encourage healing of the outer skin the preparation comes in direct contact with faster than the deeper tissue, leading to abscess. The first European settlers of America considered comfrey so indispensable, they carried it on their journey across the Atlantic in the 1600s.2. Buy 1 get 1 Half Price | Plus an extra 20% off 30, Shop buy 1 get 1 half price on all gut health products, Looking for fitness advice & inspiration this New Year? After 2-4 weeks have passed, strain the root from the alcohol using a coffee filter inserted in a wire mesh strainer or similar setup. The Comfrey Ointment that I have been using is to be used only for sprains and bruises. Koll, R., Buhr, M., Dieter, R., Pabst, H., Predel, H. G., Petrowicz, O., & Staiger, C. (2004). Brassica Campest is Seed Oil (Rapeseed Oil), Symphytum Officinale Herb (Comfrey Herb), BHA, Eucalyptus Globulus Leaf Oil (Eucalyptus Oil). Osteoarthritis Cartilage. Links to external sites are for informational purposes only. Book your free, one-to-one online consultation with one of our qualified advisors. Comfrey has been cultivated as a green vegetable and has been used as an herbal medicine for more than 2,000 years. Using different formulations together increases the risk of an overdose. It can grow up to 5 feet tall. Can a comfrey (Symphytum officianale) root extraction help ease aching joints and muscles? Koll, R., Buhr, M., Dieter, R., Petrowicz, O., Gianetti, B., and Wagener, S. Wirksamkeit und Vertraglichkeit von Beinwellextrakt (Extr. Topically, comfrey root and leaf extracts have been traditionally used for bruises, sore muscles and joints, sprains, mild wounds, and gout (Natural Medicines, 2020). Drug class: Herbal products. Phytomedicine, 11(6), 470-477. https://doi.org/10.1016/j.phymed.2004.02.001, Kucera, A., Barna, M., Holcova, S., Horacek, O., Hladikov, M., & Ottillinger, B. Its long, lance-shaped leaves can be up to 1 foot in length closer to the bottom of the stem and are shorter higher up the stem. Seal with a lid and then label with the ingredients and date. View abstract. Make sure to always buy comfrey (Symphytum officianale) root and leaf from a trusted source. Comfrey is not recommended for children under three years old, as it's not been studied in that population. Arzneimittelforschung, 62(06), 285-289. https://doi.org/10.1007/s10354-007-0474-y, Giannetti, B. M., Staiger, C., Bulitta, M., & Predel, H. G. (2010). 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Learn more in. (2001). Choose a supplement tested by a trusted third party, such as USP, ConsumerLabs, or NSF when possible. Registered office: Samuel Ryder House, Barling Way, Nuneaton, Warwickshire CV10 7RH. 4.3 4.3 out of 5 stars (225) $19.95 $ 19. Regarding its antioxidant, antilipoperoxidant, antiinflammatory, and cytotoxic properties. Comfrey has been used in alternative medicine as a possibly effective aid in treating back pain, osteoarthritis, or tenderness and swelling caused by a sprain injury. Cover, but leave a small air opening. Jedlinszki N, Balzs B, Csnyi E, Csupor D. Penetration of lycopsamine from a comfrey ointment through human epidermis. Anotherstudy found that comfrey ointment was superior to placebo in relieving pain and stiffness in osteoarthritis. Pyrrolizidine poisoning. BMJ Case Rep. 2016. Aust.Fam.Physician 2008;37(4):235-236. comfrey cream holland and barrettfeathered friend questions and answers. Using it no more than four to six weeks a year as a general guideline would be best. WMW Wiener Medizinische Wochenschrift, 154(21), 498-507. https://link.springer.com/article/10.1007/s10354-004-0114-8, Natural Medicines (2020). The use of babosa (Aloe vera) in treating burns: a literature review. Comfrey has been used medicinally for at least 2000 years for various conditions, including bone fractures, ulcers, and gout. View abstract. A limited number of clinical trials show short-term efficacy of topically applied, alkaloid-free comfrey preparations in skin abrasions and inflammatory conditions. Regul Toxicol Pharmacol. of India has issued Environment Impact Assessment EIA Notification dated 14th September, 2006 for according Environment Clearance(EC) to 8 categories of industries/projects by the Ministry of Environment & Forests, Govt. Turley, A. J. and Muir, D. F. ECG for physicians: a potentially fatal case of mistaken identity. Liver injury from herbal and dietary supplements. We cover all you need to know in this article. Complement Ther Med. Comfrey is a flowering shrub that grows in Europe, Asia and, now, North America. J Pharm.Belg. Staiger C. Comfrey root: from tradition to modern clinical trials. Comfrey has long been used in folk traditions for bruising and abrasions. Avoid with medications that induce CYP3A4 or are hepatotoxic (Natural Medicines, 2020). Be sure to use comfrey root from a reputable source that has properly identified the species. It also covers side effects, interactions, and what to look for. Electric bowl mixer (like a KitchenAid) or a blender, Small glass jars with lids for sharing (optional). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Comfrey - Memorial Sloan Kettering Cancer Center It produces clusters of purple, blue, and white flowers, and it's famous for its long . Smith DB, Jacobson BH. Jedlinszki, N., Balzs, B., Csnyi, E., & Csupor, D. (2017). Topical preparations of comfrey are generally safe provided they are not applied excessively or to an open wound. Holland Barrett | Careers Save the remaining liquid alcohol portion. What Are the Side Effects of Comfrey Cream? doi:10.1002/ptr.4612, Salehi B, Sharopov F, Boyunegmez Tumer T, et al. For that reason, Ive also included my go-to comfrey cream recipe for achy joints and muscles! Hybrids and other species may have a similar appearance but could have significantly different amounts of the toxic pyrrolizidine alkaloids (Kucera et al., 2018). comfrey cream holland and barrett - creditsolutionexperts.com J Ethnopharmacol 1995;48(2):61-76. For this reason, some topical products are advertised as made from comfrey leaves, but it's safest to choose a PA-free product. Comfrey may be used topically as a cream, ointment, salve, or paste. Registered in England: company no. Additionally, there is scientific research demonstrating comfreys effectiveness at soothing muscle and joint pain, some of which are highlighted in this post. Other prescription medicines that may harm the liver include: Some supplements may also harm the liver, including: It is essential to carefully read a supplement's ingredient list and nutrition facts panel to know which ingredients and how much of each ingredient is included. Complement Ther Clin Pract. Call your doctor for medical advice about . Herbal drugs and phytopharmaceuticals. Tolerability and effectiveness of an antitrauma cream with comfrey herb extract in pediatric use with application on intact and on broken skin. Comfrey may also be used for purposes not listed in this product guide. (2013). View abstract. Comfrey is avoided on cuts or puncture wounds for this reason. root extraction help ease aching joints and muscles? 16 Rewards for Life points with this purchase. What are the benefits of using it? Credit Solution Experts Incorporated offers quality business credit building services, which includes an easy step-by-step system designed for helping clients build their business credit effortlessly. (3), 147-156. https://doi.org/10.1016/j.jcm.2011.01.003. The plant has a long history in folk and ancient herbal treatments before comfrey is . In a randomized, double-blind, placebo-controlled trial, 220 patients with knee osteoarthritis used either a commercial topical comfrey root extract or a placebo. The most common over-the-counter medication that can be toxic to the liver is acetaminophen (Tylenol). View abstract. This is the tincture. comfrey cream holland and barrett - mail.empower.tn Yield: Approximately 5 cups of whipped lotion. Rad. Frost R, O'meara S, Macpherson H. The external use of comfrey: a practitioner survey. All rights reserved. With extract of Comfrey. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo-controlled, multicentre trial. reduce lower back pain (Stam et al., 2001). Consult with a licensed healthcare professional before using any herbal/health supplement. Recent studies have suggested topical benefits, but more research is needed. Food and Drug Administration. Influence of moderate physical exertion on subacute low back pain, after Symphytum officinale ointment treatment. Topical comfrey is for use only on the skin. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Copyright Holland & Barrett Limited 2023. You and your healthcare provider should weigh the pros and cons and use it only under their supervision. Symphytum officinale), store bought or via recipe, above. The Food and Drug Administration (FDA) released an advisory in July 2001 recommending that comfrey products be removed from the market because of cases of hepatic veno-occlusive disease.